Endocrine Abstracts

Introduction: Thyroid disorders affect metabolism and body composition; however, literature data have been conflicting on whether this is also the case for thyroid hormone levels within the euthyroid range. Therefore, we have investigated the relationship between indices of thyroid status and both body composition and metabolic parameters in a population of healthy euthyroid men.Methods: Healthy male siblings (n=941, 25–45 years, median BMI 2...

Introduction: Male gender, adolescence and obesity are known risk factors for upper limb fractures, although the mechanism by which obesity confers the increased fracture risk is unknown. In addition, most studies investigating the influence of body fat mass on bone in adolescents have been performed in school based populations using the DXA technique, which does not take into account the material and geometric bone properties.Methods: We investigated vo...

Introduction: We describe a monozygotic twin pair, of which one boy was diagnosed with anorchia. Both were followed-up till age 17.Case report: At birth, in one twin 46 XY boy (A), testes were not palpable while his brother (B) was unaffected. Stimulation with human chorionic gonadotrophin (hCG) and orchidopexia were unsuccessful at age 3. A second hCG-stimulation test was performed at age 8, where serum testosterone response failed to increase. No testi...

Context: In population and psychosocial studies, saliva becomes increasingly popular, mainly due to its non-invasive collection methods and availability of free hormone fractions. However, few studies have evaluated the impact of collection devices on steroid hormone analysis; and none with the currently used methods.Objective: The aim of this pilot study was to minimize pre-analytical errors based on sample collection methods.Meth...

Introduction: Thyroid disorders affect body composition; however, few studies have addressed the effect of variation of thyroid hormone status within the euthyroid range on body composition. Therefore, we investigated the relationship between indices of thyroid status and body composition in a population of euthyroid men.Methods: Healthy male siblings (n=677, 25–45 years, mean BMI 25.2) were recruited in a cross-sectional, population-based st...